Drug treatment of juvenile dermatomyositis.

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Drug treatment of juvenile dermatomyositis.

A series of 29 children with dermatomyositis has been reviewed and the outcome compared between cases treated by us initially with a low dosage short duration course of corticosteroids, and those referred late and having had various different therapeutic regimens and usually more active and higher dosage drug schedules. There were fewer relapses and less morbidity in the low dosage short term g...

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Treatment and clinical outcome of juvenile dermatomyositis.

Autoimmune diseases in pediatric patients are heterogeneous, including systemic lupus erythematosus, juvenile rheumatoid arthritis, and juvenile dermatomyositis (JDM). JDM is a rare autoimmune disease involving multiple body systems and accounts for 85% of idiopathic inflammatory myopathies in children. JDM may lead to death or long-term disability; therefore, investigations into the important ...

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Juvenile dermatomyositis.

Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...

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Juvenile dermatomyositis.

The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...

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Juvenile Dermatomyositis: A Review

Juvenile dermatomyositis is a systemic vasculopathy, affecting mainly the skin and muscle. In the United States, it is seen in more than three per million children per year. It is diagnosed on the basis of the criteria set by Bohan and Peter. The following review describes the characteristic clinical manifestations, the pathophysiology and immunology of the disease. The various treatment modali...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1983

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.58.6.445